{"id":435788,"date":"2020-10-20T12:36:56","date_gmt":"2020-10-20T10:36:56","guid":{"rendered":"https:\/\/hudo.com\/si\/2020\/10\/20\/britanski-znanstveniki-bodo-testno-okuzili-prostovoljce-s-koronavirusom\/"},"modified":"2021-02-05T15:03:26","modified_gmt":"2021-02-05T14:03:26","slug":"britanski-znanstveniki-bodo-testno-okuzili-prostovoljce-s-koronavirusom","status":"publish","type":"post","link":"https:\/\/hudo.com\/si\/znanost-tehnika\/britanski-znanstveniki-bodo-testno-okuzili-prostovoljce-s-koronavirusom\/","title":{"rendered":"Britanski znanstveniki bodo testno oku\u017eili prostovoljce s koronavirusom"},"content":{"rendered":"<figure><img loading=\"lazy\" decoding=\"async\" class=\"lazyload\" src=\"image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" width=\"660\" height=\"320\" \/><figcaption>foto:Profimedia<\/figcaption><\/figure>\n<p>Gre za t.i. \u0161tudije \u201c\u010dlove\u0161kega izziva\u201d (human challenge studies), ko bodo do 90 zdravih ljudi oku\u017eili z novim koronavirusom. Britanska vlada je danes potrdila, da bo za ta projekt namenila 33,6 milijona funtov, poro\u010da BBC na svoji spletni strani.<\/p>\n<h2>Je to varno?<\/h2>\n<p>Klini\u010dne preizkuse na zdravih prostovoljcih bo vodila britanska univerza Imperial College London. Izvajati naj bi jih za\u010dela januarja, a bodo pred tem morali pridobiti \u0161e odobritev eti\u010dne komisije in regulatorjev.<\/p>\n<p>Strokovnjaki trdijo, da bo varnost njihova prva prioriteta. Najprej bodo uporabili nadzorovane koli\u010dine novega koronavirusa, da bi ugotovili, katera je najmanj\u0161a koli\u010dina, ki lahko povzro\u010di oku\u017ebo. Ta preizkus bodo opravili na zdravih prostovoljcih, starih od 18 do 30 let, ki so zaradi mladosti in dobrega zdravja najmanj ogro\u017eeni, da bi jim lahko oku\u017eba \u0161kodovala. Oku\u017eili jih bodo preko nosu in bodo neprestano pod nadzorom.<\/p>\n<p>Nato bi znanstveniki lahko preizkusili, ali cepivo proti covidu-19 prepre\u010duje oku\u017ebo, navaja BBC.<\/p>\n<p>Glavni raziskovalec projekta dr. Chris Chiu z univerze Imperial College London je zatrdil, da ve\u010d kot deset let varno izvajajo \u0161tudije \u010dlove\u0161kega izziva z drugimi respiratornimi virusi.<\/p>\n<p>Priznal je, da nobena \u0161tudija ni brez tveganja, da pa bodo storili vse, da bodo zagotovili, da bo tveganje \u010dim manj\u0161e.<\/p>\n<p>Profesor eksperimentalne medicine na univerzi Peter Openshaw pa je zagotovil, da oku\u017ebe prostovoljcev z znanim patogenom niso \u201cnikoli jemali zlahka\u201d, a poudaril, da so tovrstne \u0161tudije izjemno informativne, saj je vitalnega pomena, da \u010dim prej dobimo u\u010dinkovita cepiva in druga zdravila za covid-19.<\/p>\n<p>Po svetu razvijajo ve\u010d kot sto cepiv proti covidu-19, od katerih jih je le nekaj v zaklju\u010dnih fazah testiranja, med njimi tudi cepivo Oxfordske univerze, spominja BBC.<\/p>\n<p>Ob tem navaja mnenje strokovnjaka Jonathana Van-Tama, da bi \u0161tudije \u010dlove\u0161kega izziva lahko pomagale pri izbiri najbolj obetavnih cepiv, ki so sedaj v sredini razvoja, za napredovanje v obse\u017enej\u0161a testiranja tretje faze. Pri tistih cepivih, ki so v zadnji fazi preizkusov ter dokazano varna in u\u010dinkovita, pa bi \u0161tudije \u010dlove\u0161kega izziva lahko pomagale pri razumevanju, ali cepivo prepre\u010duje prenos oku\u017ebe in obenem razvoj bolezni.<\/p>\n<p>Prvi del projekta bodo v partnerstvu izvedli univerza Imperial College London, specialisti bolni\u0161nice Royal Free Hospital in enote za raziskavo varnosti v Londonu ter podjetje hVIVO.<\/p>\n<p>Prostovoljce bodo finan\u010dno nagradili in nadzirali \u0161e do enega leta po sodelovanju v \u0161tudiji zaradi morebitnih stranskih u\u010dinkov, \u0161e navaja BBC, ki je na spletni strani objavil tudi povezavo do prijave na sodelovanje v \u0161tudiji.<\/p>\n<p>Na povezavi podjetje hVIVO navaja, da so \u0161tudije \u010dlove\u0161kega izziva doslej uporabljali pri razvoju cepiv za vrsto bolezni, med njimi za malarijo, tifus, gripo in norovirozo.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Velika Britanija naj bi postala prva dr\u017eava na svetu, kjer bodo z namenom pospe\u0161itve iznajdbe cepiva proti covidu-19 v okviru \u0161tudije znanstveniki namerno oku\u017eili zdrave prostovoljce z novim koronavirusom, da bi bolje preu\u010dili koronavirusno bolezen.<\/p>\n","protected":false},"author":1,"featured_media":435789,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18174],"tags":[15632,1643,1645],"source":[1549,1518],"supertag":[16390],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.3 - 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